Epithelioid hemangioendothelioma of the liver and pregnancy (Literature review and clinical case)

The article is devoted to the analysis of scientific publications about etiology, pathogenetic mechanisms, and management patients with epithelioid hemangioendotheliomas.Epithelioid hemangioendothelioma vascular tumor that affects liver, spleen, lungs, various other organs tissues. malignant high metastatic potential variable course. frequency it less than 0.1 per 100,000 population. etiology unknown. role molecular genetic mechanisms studied, today an association WWTR1-CAMTA1 protein in development was determined.Visual examination, computed tomography magnetic resonance imaging, which are characterized by typical signs: «white target sign», «lollipop sign» used for diagnosis. There no treatment standards hemangioendothelioma. Chemotherapy, radiofrequency ablation, surgery, liver transplantation usedOnly 8 cases during pregnancy have been described medical literature, three connected one woman. Among them: progressive negative outcomes – perinatal maternal mortality; birth a live, full-term baby; multifocal premature cesarean section sepsis mother; palate involving oropharynx child physiological terms; presacral tumor, diagnosis confirmed after pregnancy; recurrent course intracranial heart damage obstetric cases.The describes clinical case pregnant woman history resection left lobe liver. this timely diagnosis, delivery at 35 weeks satisfactory state presented. delivered male infant weighing 2500 g, height 48 cm condition. Thromboprophylaxis performed 10 days, lactation excluded.